Preclinical evaluation reveals high selectivity of [18F]T807 for paired helical filament tau, suggesting its viability as a positron emission tomography tracer for Alzheimer's disease.
[(18)F]T807 demonstrates high affinity and selectivity to PHF-tau as well as favorable in vivo properties, making this a promising candidate as an imaging agent for AD.
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Xia et al. (2013) studied this question.