Why the study?
Does vitamin B12 supplementation improve absorption in patients after vertical Roux-en-Y gastric bypass for morbid obesity?
Does vitamin B12 supplementation improve absorption in patients after vertical Roux-en-Y gastric bypass for morbid obesity?
Patients undergoing vertical Roux-en-Y gastric bypass require vitamin B12 supplementation, which can be effectively administered via monthly parenteral or daily oral crystalline preparations.
Supports B12 supplementation after vertical RYGB; leaves open optimal regimens for prospective trials.
After vertical Roux-en-Y gastric bypass for morbid obesity, acid secretion is virtually absent and food-bound vitamin B12 is maldigested and subsequently malabsorbed. The results of this study suggest that postoperative vitamin B12 supplementation is important and can be achieved with either monthly parenteral vitamin B12 or daily oral crystalline preparations.
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Smith et al. (1993) studied this question.
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