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June 2, 2015Molecular Cancer Research

Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations

John C. Hunter Anuj Manandhar Martin A. Carrasco Deepak Gurbani Sudershan Reddy Gondi Kenneth D. Westover

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Abstract

Biochemical profiling and subclassification of KRAS-driven cancers will enable the rational selection of therapies targeting specific KRAS isoforms or specific RAS effectors.

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Hunter et al. (2015) studied this question.

synapsesocial.com/papers/69de6ce4bf539e22705588d9 https://doi.org/10.1158/1541-7786.mcr-15-0203

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