Does left atrial appendage closure provide similar efficacy and safety compared to oral anticoagulants in patients with atrial fibrillation?
Left atrial appendage closure demonstrates similar efficacy and safety to oral anticoagulants (VKAs or DOACs) for patients with atrial fibrillation.
As a nonpharmacological alternative to oral anticoagulation for atrial fibrillation, LAAC showed similar efficacy and safety compared with VKAs or DOACs. Prospective confirmation from larger studies is warranted.
Oliva et al. (Fri,) studied this question.