Why the study?
Do pharmacist-initiated drug changes to reduce anticholinergic drug burden improve cognitive function in frail elderly nursing home residents?
Do pharmacist-initiated drug changes to reduce anticholinergic drug burden improve cognitive function in frail elderly nursing home residents?
Pharmacist-initiated reduction of anticholinergic drug burden does not improve cognitive function in frail elderly nursing home residents despite reducing ADS scores.
Does not support pharmacist-initiated anticholinergic deprescribing to improve cognition in frail elderly; challenges assumptions that ADS reduction yields clinical cognitive benefits.
Pharmacist-initiated drug changes significantly reduced ADS score but did not improve cognitive function in nursing home residents. Moreover, the drug changes did not reduce SAA or mouth dryness significantly, which might indicate limited applicability of the ADS score to prevent prescription risks in this population.
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Kersten et al. (2012) studied this question.
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