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October 19, 2018American Journal of PsychiatryOpen Access

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts

Sandra Sanchez‐Roige Abraham A. Palmer Pierre Fontanillas Sarah L. Elson Mark J. Adams David M. Howard Howard J. Edenberg Gail Davies Richard C. Crist Ian J. Deary Andrew M. McIntosh Toni‐Kim Clarke

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Abstract

AUDIT scores ascertained in population-based cohorts can be used to explore the genetic basis of both alcohol consumption and alcohol use disorders.

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Sanchez‐Roige et al. (2018) studied this question.

synapsesocial.com/papers/69de7b894838c5c0bab0bd1b https://doi.org/10.1176/appi.ajp.2018.18040369

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Genetic differences in alcohol sensitivity and the inheritance of alcoholism riskRisk Assessment · 1999 · 271 citations
2The heritability of alcohol use disorders: a meta-analysis of twin and adoption studiesMeta-Analysis · 2014 · 649 citations
3Genome‐wide significant association between alcohol dependence and a variant in the ADH gene clusterGWAS · 2011 · 176 citations
4Alcohol Consumption Mediates the Relationship Between <i>ADH1B</i> and DSM-IV Alcohol Use Disorder and CriteriaOriginal Research · 2014 · 13 citations
5<i>ALDH2</i> is associated to alcohol dependence and is the major genetic determinant of “daily maximum drinks” in a GWAS study of an isolated rural chinese sampleGWAS · 2013 · 117 citations

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