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October 15, 2001Angewandte Chemie International Edition40 citations

Iodoaziridine Derivatives as Novel Azahomoallyl Radical Precursors for 3+2 Cycloaddition Reactions with Alkenes

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OKOsamu KitagawaYYYoichiro YamadaHFHiroki Fujiwara

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Abstract

Functionalized pyrrolidine derivatives are accessible in good yields by radical iodine-transfer 3+2 cycloaddition of electron-rich alkenes with azahomoallyl radicals Eq. (1), which were generated by treating iodoaziridine derivatives with radical initiators. Ts=tosyl; 4-methylphenyl sulfonyl

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Kitagawa et al. (2001) studied this question.

synapsesocial.com/papers/69de7e1b210a0977fce9462ahttps://doi.org/10.1002/1521-3773(20011015)40:20<3865::aid-anie3865>3.0.co;2-5
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