February 3, 2012Open Access
Efficacy and safety of enoxaparin versus unfractionated heparin during percutaneous coronary intervention: systematic review and meta-analysis
Structured PICO
Does enoxaparin reduce mortality and bleeding outcomes compared to unfractionated heparin in patients undergoing percutaneous coronary intervention?
P
Population
Patients undergoing percutaneous coronary intervention, particularly those undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction
I
Intervention
Enoxaparin
C
Comparator
Unfractionated heparin
O
Outcome
Mortality and bleeding outcomeshard clinical
Enoxaparin may offer a mortality and safety (bleeding) advantage over unfractionated heparin during PCI, especially in the setting of primary PCI for STEMI.
Abstract
Enoxaparin seems to be superior to unfractionated heparin in reducing mortality and bleeding outcomes during percutaneous coronary intervention and particularly in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction.