Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds

Anthony J. Griswold; Katrina Celis; Parker L. Bussies; Farid Rajabli; Patrice L. Whitehead; Kara L. Hamilton‐Nelson; Gary W. Beecham; Derek M. Dykxhoorn; Karen Nuytemans; Liyong Wang; Olivia K. Gardner; Daniel A. Dorfsman; Eileen H. Bigio; Marek Marsel Mesulam; Sandra Weıntraub; Changiz Geula; Marla Gearing; Elisa Mcgrath‐Martinez; Clifton L. Dalgard; William K. Scott; Jonathan L. Haines; Margaret A. Pericak‐Vance; Juan I. Young; Jeffery M. Vance

doi:10.1002/alz.12287

Abstract

AD patients with ELA expressed significantly greater levels of APOE than ALA APOE ε4 carriers. These differences in APOE expression could contribute to the reduced risk for AD seen in African APOE ε4 carriers.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Griswold et al. (2021) studied this question.

synapsesocial.com/papers/69de84666bae133e7de93974 https://doi.org/10.1002/alz.12287

View Full Paper

Ask AI

Bookmark

Share

Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds

Abstract

Discussion

Cite This Study

Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds

Abstract

Discussion

Cite This Study

Keep reading

Keep reading