Discretization methods to round an approximate design into an exact design for a given sample size n are discussed.There is a unique method, called efficient rounding, which has the smallest loss of efficiency under a wide family of optimality criteria.The efficient rounding method is a multiplier method of apportionment which otherwise is known as the method of John Quincy Adams or the method of smallest divisors.
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Pukelsheim et al. (1992) studied this question.
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