Why the study?
Are single nucleotide polymorphisms in thrombospondin genes associated with familial premature myocardial infarction?
Are single nucleotide polymorphisms in thrombospondin genes associated with familial premature myocardial infarction?
Genetic variants in the thrombospondin gene family may play a role in familial premature myocardial infarction, highlighting a potential area for further genomic study.
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No immediate clinical implications for familial premature MI; leaves open a genetic association requiring replication in larger cohorts.
Topol et al. (2001) studied this question.
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