August 7, 2015The Journal of PhysiologyOpen Access

What limits performance during whole‐body incremental exercise to exhaustion in humans?

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Why the study?

Does incremental exercise task failure result from metabolite accumulation or lack of energy resources in humans?

Population

22 men (age 22 ± 3 years)

Comparison

Incremental exercise to exhaustion followed by… vs Control and comparisons between recovery…

Design

Random order for recovery conditions

Authors

DMDavid Morales‐ÁlamoUniversidad de Las Palmas de Gran Canaria JLJosé Losa‐ReynaUniversidad de Valladolid RTRafael Torres‐PeraltaUniversidad Politécnica de Madrid

Discussion

Member takes

Implication

Central mechanisms should guide models of incremental exercise tolerance; leaves open peripheral contributions in clinical or diseased states.

Structured PICO

Does incremental exercise task failure result from metabolite accumulation or lack of energy resources in humans?

Population

22 men (age 22 ± 3 years)

Intervention

Incremental exercise to exhaustion (IE) followed by 10 or 60 s recovery with open circulation or bilateral leg occlusion (300 mmHg) in normoxia (P(IO2) 143 mmHg) or hypoxia (P(IO2): 73 mmHg), then a 10 s all-out isokinetic sprint

Comparator

Control (before IE) and comparisons between recovery durations (10 vs 60 s), circulation (open vs occluded), and oxygenation (normoxia vs hypoxia)

Outcome

Sprint performance (peak power output, W(peak)) and muscle metabolites (lactate, phosphocreatine, ATP)surrogate

Task failure during incremental exercise is primarily determined by central mechanisms rather than peripheral metabolite accumulation or energy depletion.

Cite This Study

Morales‐Álamo et al. (2015) studied this question.

synapsesocial.com/papers/69de87fbbf539e2270558fd7 https://doi.org/10.1113/jp270487

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Implication

Central mechanisms should guide models of incremental exercise tolerance; leaves open peripheral contributions in clinical or diseased states.

What limits performance during whole‐body incremental exercise to exhaustion in humans?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

What limits performance during whole‐body incremental exercise to exhaustion in humans?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider