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January 15, 2016BMC GeriatricsOpen Access

The association of serum procalcitonin and high-sensitivity C-reactive protein with pneumonia in elderly multimorbid patients with respiratory symptoms: retrospective cohort study

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Why the study?

Does serum hs-CRP testing improve the diagnosis of pneumonia compared to procalcitonin testing in elderly multimorbid patients admitted for respiratory symptoms?

Population

Elderly multimorbid patients who require hospital admission for respiratory symptoms

Comparison

Serum high-sensitivity C-reactive protein testing vs Serum procalcitonin testing

Design

Cohort

Authors

ANAntonio NouvenneUniversity of ParmaATAndrea TicinesiUniversity of ParmaGFGiuseppina FolesaniIstituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro

Discussion

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Implication

May favor hs-CRP over procalcitonin for pneumonia diagnosis in elderly multimorbid patients; leaves open need for RCTs before practice change.

Structured PICO

Does serum hs-CRP testing improve the diagnosis of pneumonia compared to procalcitonin testing in elderly multimorbid patients admitted for respiratory symptoms?

P
Population
Elderly multimorbid patients who require hospital admission for respiratory symptoms
I
Intervention
Serum high-sensitivity C-reactive protein (hs-CRP) testing
C
Comparator
Serum procalcitonin testing
O
Outcome
Diagnosis of pneumonia

In elderly multimorbid patients admitted with respiratory symptoms, hs-CRP testing is more useful than procalcitonin for diagnosing pneumonia.

Cite This Study

Nouvenne et al. (2016) studied this question.

synapsesocial.com/papers/69dea574077ec87fd1e93ab0https://doi.org/10.1186/s12877-016-0192-7
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hazzard’s Geriatric Medicine and Gerontology2009 · 524 citations
  2. 2A Manual of Guidelines to Score the Modified Cumulative Illness Rating Scale and Its Validation in Acute Hospitalized Elderly Patients2008 · 596 citations