CD200 promotes immunosuppression in the pancreatic tumor microenvironment

Fouad Choueiry; Molly Torok; Reena Shakya; Kriti Agrawal; Anna Deems; Brooke Benner; Alice Hinton; Jami Shaffer; Bradley W. Blaser; Anne M. Noonan; Terence M. Williams; Mary Dillhoff; Darwin L. Conwell; Phil A. Hart; Zobeida Cruz‐Monserrate; Xue‐Feng Bai; William E. Carson; Thomas A. Mace

doi:10.1136/jitc-2019-000189

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Abstract

These results indicate that CD200 expression in the PDAC microenvironment may regulate MDSC expansion and that targeting CD200 may enhance activity of checkpoint immunotherapy.

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Choueiry et al. (2020) studied this question.

synapsesocial.com/papers/69deaac5210a0977fce950bc https://doi.org/10.1136/jitc-2019-000189

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CD200 promotes immunosuppression in the pancreatic tumor microenvironment

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Abstract

Discussion

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CD200 promotes immunosuppression in the pancreatic tumor microenvironment

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Abstract

Discussion

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