Why the study?
Do NOACs improve efficacy and safety compared with VKAs in patients with nonvalvular atrial fibrillation and concomitant aspirin therapy?
Do NOACs improve efficacy and safety compared with VKAs in patients with nonvalvular atrial fibrillation and concomitant aspirin therapy?
In patients with nonvalvular atrial fibrillation on concomitant aspirin therapy, NOACs may offer a safer and more effective alternative to VKAs.
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NOACs may be preferred over VKAs in nonvalvular AF with aspirin; extends RCT evidence to this dual-therapy subgroup.
This study-based meta-analysis shows that it may be both safer and more effective to use NOACs compared with VKAs to treat patients with nonvalvular atrial fibrillation and concomitant aspirin therapy.
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Bennaghmouch et al. (2017) studied this question.
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