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October 12, 2016New England Journal of Medicine638 citations

Cardiovascular Toxic Effects of Targeted Cancer Therapies

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JMJavid J. Moslehi

Structured PICO

I
Intervention
Targeted cancer therapies (agents targeting signaling pathways in cancer cells)
O
Outcome
Cardiovascular toxic effectssafety

Targeted cancer therapies are associated with cardiovascular toxicities such as decreased ejection fraction and atrial arrhythmias.

Abstract

Agents targeting signaling pathways in cancer cells are less specific than advertised. A number of these agents induce cardiovascular toxic effects ranging from decreased ejection fraction to atrial arrhythmias.

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Cite This Study

Javid J. Moslehi (2016) studied this question.

synapsesocial.com/papers/69deb3b740ea06567955928ahttps://doi.org/10.1056/nejmra1100265
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