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November 10, 2004Molecular Biology and EvolutionOpen Access

CpG Mutation Rates in the Human Genome Are Highly Dependent on Local GC Content

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KFKarl J. FryxellGeorge Mason UniversityWMWonjong MoonSt. Jude Children's Research Hospital

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Fryxell et al. (2004) studied this question.

synapsesocial.com/papers/69deb7d27702a00918b0c91chttps://doi.org/10.1093/molbev/msi043
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cytosine Deamination Plays a Primary Role in the Evolution of Mammalian Isochores2000 · 222 citations
  2. 2The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model.1990 · 391 citations
  3. 3A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy1990 · 509 citations