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February 1, 1996New England Journal of Medicine2,709 citationsOpen Access

A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension

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RBRobyn J. BarstLRLewis J. RubinWLWalker Long

Structured PICO

Does continuous intravenous epoprostenol improve symptoms, hemodynamics, and survival in patients with severe primary pulmonary hypertension?

P
Population
patients with severe primary pulmonary hypertension
I
Intervention
continuous intravenous infusion of epoprostenol
C
Comparator
conventional therapy
O
Outcome
symptomatic and hemodynamic improvement, and survival

Continuous intravenous epoprostenol improves survival, symptoms, and hemodynamics in patients with severe primary pulmonary hypertension compared to conventional therapy.

Abstract

As compared with conventional therapy, the continuous intravenous infusion of epoprostenol produced symptomatic and hemodynamic improvement, as well as improved survival in patients with severe primary pulmonary hypertension.

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Cite This Study

Barst et al. (1996) studied this question.

synapsesocial.com/papers/69debee95e217d93a55584bdhttps://doi.org/10.1056/nejm199602013340504
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