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April 1, 2002Journal of Applied Physiology

Capillary supply of the tibialis anterior muscle in young, healthy, and moderately active men and women

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Authors

MPMichelle M. PorterUniversity of TorontoSSS. K. StuartUniversity of ManitobaMBM. BoijLund University

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Implication

Comparative study demonstrates equivalent overall muscle capillarization between active young men and women despite differences in fiber size, suggesting comparable baseline microvascular supply.

Key Points

  • To investigate whether sex differences exist in capillarization and fiber morphology within the tibialis anterior muscle of young, healthy adults.
  • Examined tibialis anterior muscle biopsies obtained from young, moderately active men and women aged 21–30 years (n = 30).
  • Assessed fiber type distribution, fiber cross-sectional area, capillary density (CD), capillary-to-fiber ratio (C/F), capillary contacts (CC), fiber area per capillary (FA/C), and fiber perimeter per capillary (FP/C).
  • Men had significantly larger muscle fibers than women (P < 0.001) and a higher capillary-to-fiber ratio (2.20 ± 0.35 vs. 1.66 ± 0.32; P < 0.01), which was accounted for by muscle fiber size.
  • Capillary density was equivalent between groups at approximately 390 capillaries/mm², and fiber area per capillary showed no sex differences for type I or type II fibers.
  • Type II fiber perimeter per capillary differed significantly between sexes, measuring 60.5 ± 10.9 in men versus 70.6 ± 13.4 in women (P < 0.01).

Cite This Study

Porter et al. (2002) studied this question.

synapsesocial.com/papers/69debfb1499d77a496b0cbb2https://doi.org/10.1152/japplphysiol.00744.2001
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Also Consider

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