On‐Chip Synthesis and Label‐Free Assays of Oligosaccharide Arrays

Sugar coated: A new strategy for solid-support oligosaccharide array synthesis and direct SAMDI-TOF (self-assembled monolayers for matrix-assisted laser desorption-ionization time-of-flight) mass spectrometry detection of the synthesis process is reported (see scheme). It incorporates an on-chip ligand array synthesis, a label-free detection method, and direct application to an enzymatic assay. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z704998_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.