Why the study?
Does previous silent myocardial infarction predict poorer long-term clinical outcomes in patients presenting with first AMI?
Does previous silent myocardial infarction predict poorer long-term clinical outcomes in patients presenting with first AMI?
Previous silent MI identifies a high-risk subgroup of patients presenting with first AMI, with a >3-fold risk of mortality and MACE.
Supports risk stratification by prior silent MI in first AMI; leaves open whether detection improves outcomes.
Silent MI occurred in 8.2% of patients presenting with first AMI and was independently related to poorer long-term clinical outcome, with a more than 3-fold risk of mortality and MACE. Silent MI holds prognostic value over important traditional prognosticators in the setting of AMI, indicating that these patients represent a high-risk subgroup warranting clinical awareness.
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Amier et al. (2018) studied this question.
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