Why the study?
What are the maternal haemodynamic changes and responses to phenylephrine during spinal anaesthesia for caesarean section?
What are the maternal haemodynamic changes and responses to phenylephrine during spinal anaesthesia for caesarean section?
Heart rate response to vasopressors is a useful surrogate marker for cardiac output during spinal anaesthesia for caesarean section.
Heart rate response may guide vasopressor use in caesarean spinal anaesthesia; leaves open prospective validation before practice change.
The most frequent response to spinal anaesthesia for elective caesarean section is a marked decrease in systemic vascular resistance and partial compensation from increased stroke volume and heart rate. Early administration of phenylephrine by bolus or continuous infusion is indicated in most cases. Recent work has expanded our knowledge of the therapeutic range of phenylephrine and indicates that the heart rate response to vasopressors is a good surrogate marker for cardiac output. Further research should examine haemodynamic changes during spinal anaesthesia in high-risk pregnant women with early onset preeclampsia or cardiac disease.
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Langesæter et al. (2011) studied this question.
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