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December 23, 2005Gut413 citationsOpen Access

Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn’s disease: a randomised, double blind, placebo controlled GETAID trial

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PMPhilippe MarteauMLMarc LémannPSPhilippe Seksik

Key Points

  • This trial aims to evaluate the efficacy of Lactobacillus johnsonii LA1 in preventing postoperative recurrence of Crohn's disease.
  • Randomized double-blind placebo-controlled trial
  • Involved administration of Lactobacillus johnsonii LA1 (4 x 10(9) cfu/day)
  • Participants monitored for endoscopic recurrence of Crohn's disease.
  • Lactobacillus johnsonii LA1 did not demonstrate a significant effect on preventing endoscopic recurrence of Crohn's disease.
  • No sufficient evidence found for effectiveness compared to placebo.

Abstract

L johnsonii LA1 (4 x 10(9) cfu/day) did not have a sufficient effect, if any, to prevent endoscopic recurrence of Crohn's disease.

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Cite This Study

Marteau et al. (2005) studied this question.

synapsesocial.com/papers/69df12f0b46aaead81614293https://doi.org/10.1136/gut.2005.076604
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