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April 15, 2026Alzheimer s & Dementia0 citationsOpen Access

Associations between parental history of dementia and plasma markers of inflammation in a multi‐ethnic middle‐aged community of adults

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EWEdric WinfordUniversity of KentuckyBHBenjamin D. HuberColumbia UniversityDŠDominika ŠeblováCharles University

Key Points

  • This research aims to explore the link between parental history of dementia and levels of inflammation markers in adults.
  • Examined plasma markers of inflammation in a diverse community of middle-aged adults.
  • Analyzed the influence of parental dementia history on inflammation levels.
  • Considered variations in results across different sexes and ethnicities.
  • Found elevated inflammation markers in adults with a parental history of dementia.
  • Noted differences in associations based on sex and ethnicity.
  • Indicated that race may influence the relationship between familial dementia history and inflammation.

Abstract

Parental history of dementia is associated with elevated markers of peripheral inflammation. These associations vary across sex, race, and ethnicity.

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Cite This Study

Winford et al. (2026) studied this question.

synapsesocial.com/papers/69df2b49e4eeef8a2a6b03dchttps://doi.org/10.1002/alz.71355
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