Demonstrates the role of EnvZ in regulating antibiotic resistance and virulence traits in E. coli, suggesting potential therapeutic targets.
EnvZ regulates β-lactam resistance by modulating porin expression and membrane permeability, while also influencing virulence traits like adhesion and motility. These findings highlight TCS-mediated resistance mechanisms and offer potential targets for novel antimicrobials or vaccines against E. coli.
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Yang et al. (2026) studied this question.
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