Prognostic Evaluation of Nephroblastoma in Senegal: Experience of a Regional Reference Center with 42 Cases

Nephroblastoma, or Wilms tumor, is the most common malignant kidney tumor in children, accounting for 5 to 10% of pediatric cancers [1]. In developed countries, survival rates exceed 90% thanks to multimodal treatment protocols established by the International Society of Pediatric Oncology (SIOP) and the National Wilms Tumor Study Group (NWTSG) [2,3]. In sub-Saharan Africa, the management of this disease faces specific challenges related to diagnostic delays, socio-economic constraints, and limited access to specialized care [4,5]. The Franco-African Pediatric Oncology Group (GFAOP) has initiated the adaptation of SIOP protocols to the African context, demonstrating their feasibility and effectiveness [6,7]. Our study aims to evaluate the experience of the Thiès Regional Hospital Center in the management of nephroblastoma by analyzing epidemiological, therapeutic, and prognostic aspects in a decentralized healthcare context similar to the challenges reported in other developing countries [8].