Minimizing Early-Onset Lymphedema Following Groin Dissection in Metastatic Melanoma

Melody C. Brown; T. S. Lee; Isabel Li; Christopher Allan

doi:10.1245/s10434-026-19559-4

April 13, 2026Annals of Surgical OncologyOpen Access

Minimizing Early-Onset Lymphedema Following Groin Dissection in Metastatic Melanoma

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Key Points

The aim is to evaluate the effectiveness of interventions in reducing early-onset lymphedema following groin dissection for melanoma.
Compared the effects of custom-garment soft lymphedema intervention with standard care over 24 months.
Evaluated lymphedema incidence and severity at multiple time points, particularly at 6 and 24 months post-intervention.
No significant difference in lymphedema incidence was found between interventions at 24 months.
Early reductions in lymphedema incidence were noted but did not last beyond 6 months after treatment completion.

Implication

Reports on lymphedema incidence after groin dissection in melanoma, suggesting further research is needed for effective prevention.

Abstract

CG-SLD did not reduce lymphedema incidence compared with SC at 24 months. Although early reductions in lymphedema incidence and severity were observed for CG-SLD, these were not maintained beyond 6 months when interventions ceased. The study was underpowered, and larger trials are required to determine whether early prophylactic strategies provide durable benefit.

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Cite This Study

Brown et al. (2026) studied this question.

synapsesocial.com/papers/69df2c50e4eeef8a2a6b1473 https://doi.org/10.1245/s10434-026-19559-4

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Minimizing Early-Onset Lymphedema Following Groin Dissection in Metastatic Melanoma

Key Points

Implication

Abstract

Discussion

Cite This Study

Minimizing Early-Onset Lymphedema Following Groin Dissection in Metastatic Melanoma

Key Points

Implication

Abstract

Discussion

Cite This Study

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