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March 16, 2016Arthritis Research & TherapyOpen Access

Generation mechanism of RANKL+ effector memory B cells: relevance to the pathogenesis of rheumatoid arthritis

Yuri Ota Hiroaki Niiro Shun-ichiro Ota Naoko Ueki Hirofumi Tsuzuki Tsuyoshi Nakayama Koji Mishima Kazuhiko Higashioka Siamak Jabbarzadeh‐Tabrizi Hiroki Mitoma Mitsuteru Akahoshi Yojiro Arinobu Akiko Kukita Hisakata Yamada Hiroshi Tsukamoto Koichi Akashi

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Abstract

Our current findings have shed light on the generation mechanism of pathogenic RANKL(+) effector B cells that would be an ideal therapeutic target for rheumatoid arthritis in the future.

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Ota et al. (2016) studied this question.

synapsesocial.com/papers/69df3d6635659245ec61427b https://doi.org/10.1186/s13075-016-0957-6

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