Why the study?
Does excessive crystalloid infusion (>10.5 L over 72 hours) increase the risk of anastomotic leakage in trauma patients undergoing primary colocolonic anastomosis?
Does excessive crystalloid infusion (>10.5 L over 72 hours) increase the risk of anastomotic leakage in trauma patients undergoing primary colocolonic anastomosis?
Excessive crystalloid infusion (>10.5 L in the first 72 hours) after trauma laparotomy with colon resection is associated with a significantly increased risk of anastomotic leakage.
May support fluid-restrictive strategies after trauma laparotomy; leaves open prospective validation of this threshold.
Increased use of crystalloids after primary colocolonic anastomosis at initial trauma laparotomy is associated with anastomotic leakage. A threshold of 10.5 L of crystalloid fluid infused over the first 72 hours is associated with a 5-fold increased risk for colocolonic suture line failure. The impact of crystalloid restriction on anastomotic failure in trauma patients warrants prospective investigation.
No takes yet. Share an insight, caveat, or question.
Schnüriger et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: