Why the study?
Does atorvastatin 40 mg/d initiated 7 days before surgery reduce the incidence of postoperative atrial fibrillation in patients undergoing elective cardiac surgery with cardiopulmonary bypass?
Does atorvastatin 40 mg/d initiated 7 days before surgery reduce the incidence of postoperative atrial fibrillation in patients undergoing elective cardiac surgery with cardiopulmonary bypass?
Preoperative atorvastatin reduces postoperative atrial fibrillation and shortens hospital stay in patients undergoing elective cardiac surgery.
Supports preoperative atorvastatin in elective cardiac surgery; extends perioperative AF prevention evidence.
Treatment with atorvastatin 40 mg/d, initiated 7 days before surgery, significantly reduces the incidence of postoperative AF after elective cardiac surgery with cardiopulmonary bypass and shortens hospital stay. These results may influence practice patterns with regard to adjuvant pharmacological therapy before cardiac surgery.
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Patti et al. (2006) studied this question.
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