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To the Editor: In our meta-analysis 1 of studies in which the effects of psychotherapy and pharmacotherapy for adult depression were compared directly to each other, we found a trend that pharmacotherapy may be somewhat more effective than psychotherapy (P < .1), that SSRIs were more effective than psychotherapy (P < .01), and that dropout rates in pharmacotherapy were higher than in psychotherapy (P < .05). It is possible that the finding that pharmacotherapy is superior is the result of the higher dropout rates with pharmacotherapy. We did not examine this possibility in our earlier study.
Cuijpers et al. (Wed,) studied this question.