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July 23, 2004Journal of Thoracic and Cardiovascular Surgery224 citationsOpen Access

Toll-like receptor 4 mediates ischemia/reperfusion injury of the heart

ACAlbert J. ChongSeattle Pacific UniversityASAkira ShimamotoMie UniversityCHCraig R. HamptonSeattle Pacific University

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Abstract

Our data suggest that toll-like receptor 4 may mediate, at least in part, myocardial ischemia/reperfusion injury. Inhibition of toll-like receptor 4 activation may be a potential therapeutic target to attenuate ischemia/reperfusion-induced tissue damage in the clinical setting.

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Chong et al. (2004) studied this question.

synapsesocial.com/papers/69df3f2144b0122c4f7a10b2https://doi.org/10.1016/j.jtcvs.2003.11.036
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