Identification of novel ruminant pestiviruses closely related to CSFV highlights the potential for diagnostic cross-reactivity in pigs.
May indicate CSFV diagnostic cross-reactivity risks; leaves open the epidemiology and control implications of these novel pestiviruses.
To determine why serum from small ruminants infected with ruminant pestiviruses reacted positively to classical swine fever virus (CSFV)-specific diagnostic tests, we analyzed 2 pestiviruses from Turkey. They differed genetically and antigenically from known Pestivirus species and were closely related to CSFV. Cross-reactions would interfere with classical swine fever diagnosis in pigs.
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Postel et al. (2015) studied this question.
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