Non-thermal plasma jet without electrical shock for biomedical applications

A plasma jet without an electrical shock was generated through a Y-shaped tube in which voltages with opposite phases were applied to a pair of tubes. The plasma plume generated at the intersection had a plasma potential of a 60–90 V and high concentrations of reactive species sufficient to induce a high level of lethality on gram-negative bacteria on a tissue mimic. The selective lethality of bacteria on an epithelial-cell-containing tissue mimic could be modulated using oxidant and antioxidant chemicals, thereby leading to the possibility of a shock-reduced plasma jet for biomedical applications.