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January 1, 2015World Journal of GastroenterologyOpen Access

Berberine inhibits hepatic gluconeogenesisviathe LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats

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Abstract

To investigate the molecular mechanisms of berberine inhibition of hepatic gluconeogenesis in a diabetic rat model.

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Cite This Study

Shujun Jiang (2015) studied this question.

synapsesocial.com/papers/69df4ef0d5404a0bea592e8b https://doi.org/10.3748/wjg.v21.i25.7777

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Hepatic glucose uptake, gluconeogenesis and the regulation of glycogen synthesisOriginal Research · 2001 · 269 citations
2The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of MetforminOriginal Research · 2005 · 1,950 citations
3Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic GluconeogenesisOriginal Research · 2011 · 263 citations
4Beneficial effect of berberine on hepatic insulin resistance in diabetic hamsters possibly involves in SREBPs, LXR.ALPHA. and PPAR.ALPHA. transcriptional programsOriginal Research · 2010 · 57 citations
5Berberine Regulated Gck, G6pc, Pck1 and Srebp-1c Expression and Activated AMP-activated Protein Kinase in Primary Rat HepatocytesOriginal Research · 2011 · 37 citations

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