We have shown that most people stop taking PrEP before their second PrEP refill and individuals >24 years had longer PrEP persistence than individuals aged 15-19 years. Service delivery factors appear to have a substantial effect on PrEP persistence. Health facilities should continue to make PrEP accessible by integrating PrEP with existing services to promote PrEP persistence.
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Shangase et al. (2025) studied this question.
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