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September 25, 2012Journal of Clinical OncologyOpen Access

Association Between Circulating Tumor Cells and Prognosis in Patients With Stage III Melanoma With Sentinel Lymph Node Metastasis in a Phase III International Multicenter Trial

Sojun Hoshimoto Tatsushi Shingai Donald L. Morton Christine Kuo Mark B. Faries Kelly K. Chong David Elashoff Hong Wang Robert M. Elashoff Dave S.�B. Hoon

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Abstract

CTC biomarker status is a prognostic factor for recurrence-free survival, distant metastasis disease-free survival, and MSS after CLND in patients with SLN metastasis. This multimarker RT-qPCR analysis may therefore be useful in discriminating patients who may benefit from aggressive adjuvant therapy or stratifying patients for adjuvant clinical trials.

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Hoshimoto et al. (2012) studied this question.

synapsesocial.com/papers/69df72266324afb55d592a9d https://doi.org/10.1200/jco.2011.40.0887

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