To translate new and advanced materials into clinical use more quickly, the clinical relevance and validity of preclinical tests need to be improved. To achieve this for PEEK-based devices, human tissue retrieval studies including subsequent particle isolation and characterization analyses are required. In vitro cell studies using isolated wear particles from tissue or validated joint replacement simulators, instead of manufactured particles, are also required.
No takes yet. Share an insight, caveat, or question.
Stratton‐Powell et al. (2016) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: