Does substitution of Primex with palm oil in GAN diet promote a similar phenotype of biopsy-confirmed NASH in ob/ob and C57BL/6J mice?
GAN diet-induced obese mouse models using palm oil instead of Primex are suitable for characterizing novel NASH treatments.
Substitution of Primex with palm oil promotes a similar phenotype of biopsy-confirmed NASH in ob/ob and C57BL/6J mice, making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments.
Boland et al. (Wed,) studied this question.