Why the study?
Does l-Citrulline supplementation attenuate aortic haemodynamic and arterial stiffness responses to metaboreflex and cold stress in healthy overweight/obese men?
Population
16 healthy, overweight/obese males (mean age 24 years; mean BMI 29.3 kg/m2)
Comparison
l-Citrulline 6 g/d for 14 days vs Placebo for 14 days (cross-over design)
Design
RCT, Randomly assigned in a cross-over design
Follow-up
14 days
Authors
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May blunt stress-induced cardiac afterload in overweight men; extends citrulline vascular data to acute combined metaboreflex-cold stimuli.
Does l-Citrulline supplementation attenuate aortic haemodynamic and arterial stiffness responses to metaboreflex and cold stress in healthy overweight/obese men?
Short-term l-Citrulline supplementation attenuates aortic blood pressure and arterial stiffness responses to physical stress in overweight men, suggesting a protective effect against increased cardiac afterload.
Figueroa et al. (2016) studied this question.
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