Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa

Meryem Jafari; Abdelilah Laraqui; Walid Baba; Soukaina Benmokhtar; Sara El Zaitouni; Abdelmounaïm Ait Ali; Ahmed Bounaim; Mountassir Moujahid; Rachid Tanz; Tarik Mahfoud; Yassir Sbitti; Hicham El Annaz; Rachid Abi; Mohamed Rida Tagajdid; Safae El Kochri; Idriss Amine Lahlou; Houda El Hsaïni; Lamiae Belayachi; Abdelaziz Benjouad; Mohammed Ichou; Amina En-Nya; Khalid Ennibi

doi:10.1186/s12885-022-10235-w

Abstract

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KRAS mutated CRC patients in North Africa have been identified with incidence closer to the European figures. Beside established anti-CRC treatment, better understanding of the causality of CRC can be established by combining epidemiology and genetic/epigenetic on CRC etiology. This approach may be able to significantly reduce the burden of CRC in North Africa.

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Jafari et al. (2022) studied this question.

synapsesocial.com/papers/69dff5a12833447a7e255584 https://doi.org/10.1186/s12885-022-10235-w

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa

Abstract

Discussion

Cite This Study

Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa

Abstract

Discussion

Cite This Study

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