Cortical thickness is a more sensitive marker for detecting pervasive cortical atrophy in Motoric Cognitive Risk Syndrome compared to volume or surface area.
Cortical thickness may refine atrophy assessment in MCR; leaves open its value for progression prediction or clinical decisions.
Cortical atrophy in MCR is pervasive, and include regions previously associated with human locomotion, but also social, cognitive, affective, and motor functions. Cortical atrophy in MCR is easier to detect in cortical thickness than volume and surface area because thickness is more affected by healthy and pathological aging.
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Blumen et al. (2021) studied this question.
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