Reversibly Addressing an Allosteric Catalyst In Situ: Catalytic Molecular Tweezers

Abiotic allosteric regulation: The design, synthesis, and application of novel, reversible allosteric catalytic molecular tweezers that contain a structural metal, addressable in situ, and two functional catalytic metals are reported (see picture). Kinetic and selectivity data reflect a significant decrease in cooperativity upon opening of the “arms” of the catalyst caused by reactions occurring at the hinge. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z460932_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.