Does percutaneous hemodynamic support with Impella 2.5 improve safety and hemodynamics compared to pharmacological agents alone during scar-related ventricular tachycardia ablation in patients with severe left ventricular dysfunction?
Impella 2.5 support during scar-related VT ablation in patients with severe LV dysfunction is safe, feasible, and provides better hemodynamic support than pharmacological agents alone.
In a consecutive series of patients with severe left ventricular dysfunction, pLVAD-supported scar VT ablation was safe and feasible. During fast simulated VT, a miniaturized axial flow pump imparted a more favorable hemodynamic profile compared with pharmacological agents alone. Cerebral oximetry is a complimentary monitoring modality during scar VT ablation, and avoidance of cerebral desaturations below a threshold of 55% may safely guide the duration of mapping during unstable VT.
Miller et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: