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February 1, 1983Anesthesia & Analgesia

Thromboembolism after Total Hip Replacement

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Why the study?

Does continuous epidural anesthesia reduce the incidence of thromboembolism compared to general anesthesia in patients undergoing total hip replacement?

Population

60 patients undergoing total hip replacement

Comparison

Continuous epidural anesthesia vs General anesthesia

Design

RCT, randomly allotted to one of two groups

Authors

JMJ. ModigTBT. BorgGMG ran Karlstr m

Discussion

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Overview

Supports epidural anesthesia to reduce thromboembolism after hip replacement; confirms regional anesthesia superiority in this RCT.

Structured PICO

Does continuous epidural anesthesia reduce the incidence of thromboembolism compared to general anesthesia in patients undergoing total hip replacement?

P
Population
60 patients undergoing total hip replacement
I
Intervention
Continuous epidural anesthesia (0.5% bupivacaine with epinephrine intraoperatively; 0.25% bupivacaine with epinephrine every 3 h for 24 h postoperatively)
C
Comparator
General anesthesia (controlled ventilation with N2O-O2, intravenous fentanyl and pancuronium bromide intraoperatively; intramuscular narcotic analgesics on demand postoperatively)
O
Outcome
Incidence of thromboembolism (deep venous thrombosis and pulmonary embolism)hard clinical

Continuous epidural anesthesia significantly reduces the incidence of deep venous thrombosis and pulmonary embolism following total hip replacement compared to general anesthesia.

Cite This Study

Modig et al. (1983) studied this question.

synapsesocial.com/papers/69e0028293e101b251e9c697https://doi.org/10.1213/00000539-198302000-00010
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