Why the study?
Is impaired coronary flow velocity reserve (CFVR) associated with cardiovascular risk factors, symptoms, or stress testing results in women with angina pectoris and no obstructive coronary artery disease?
Is impaired coronary flow velocity reserve (CFVR) associated with cardiovascular risk factors, symptoms, or stress testing results in women with angina pectoris and no obstructive coronary artery disease?
Coronary microvascular dysfunction is common in women with angina and no obstructive CAD, but cannot be reliably identified by traditional risk factors, symptoms, or standard stress testing.
Answers are grounded in this paper and cite their sources.
Standard tools may miss impaired CFVR in women with angina and no obstructive CAD; leaves open need for direct microvascular assessment in trials.
Impaired CFVR was detected in a substantial proportion, which suggests that coronary microvascular dysfunction plays a role in the development of angina pectoris. CFVR was associated with few cardiovascular risk factors, suggesting that CFVR is an independent parameter in the risk evaluation of these women. Symptom characteristics and results from stress testing did not identify individuals with impaired CFVR.
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Mygind et al. (2016) studied this question.
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