Why the study?
Does long-term cigarette smoking impair endothelium-dependent coronary vasodilation?
Does long-term cigarette smoking impair endothelium-dependent coronary vasodilation?
Long-term cigarette smoking impairs endothelium-dependent coronary vasodilation, independent of coronary atherosclerosis.
Smoking may impair coronary endothelial function independent of atherosclerosis; leaves open reversibility after cessation and needs prospective trials.
Long-term cigarette smoking is associated with impaired endothelium-dependent coronary vasodilation regardless of the presence or absence of coronary atherosclerotic lesions.
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Zeiher et al. (1995) studied this question.
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