Randomized trial reveals increased bone mineral density and decreased bone resorption with denosumab in postmenopausal women, suggesting its efficacy as an osteoporosis treatment.
In postmenopausal women with low bone mass, denosumab increased bone mineral density and decreased bone resorption. These preliminary data suggest that denosumab might be an effective treatment for osteoporosis. (ClinicalTrials.gov number, NCT00043186.).
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McClung et al. (2006) studied this question.
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