Why the study?
Is TPCR a more sensitive screening test than ACR to predict clinically relevant proteinuria in patients with chronic kidney disease?
Is TPCR a more sensitive screening test than ACR to predict clinically relevant proteinuria in patients with chronic kidney disease?
TPCR is a more sensitive screening test than ACR for predicting clinically relevant proteinuria in patients with non-diabetic CKD, suggesting caution when using ACR alone.
Caution against ACR-only screening in CKD; leaves open whether TPCR improves outcomes pending prospective validation.
TPCR is a more sensitive screening test than ACR to predict clinically relevant proteinuria. The diagnostic performance of both tests varies substantially with age and gender, and should be taken into consideration when interpreting results. Total proteinuria cannot be adequately predicted from ACR, and our results suggest that caution is appropriate before utilizing ACR in patients with non-diabetic CKD.
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Methven et al. (2010) studied this question.
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