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April 16, 2026Human Vaccines & Immunotherapeutics0 citationsOpen Access

Cognitive factors associated with willingness to receive three important vaccines among older adults: A protection motivation theory perspective

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XPXueqing PengRHRongna HuangAWAnita Nyarkoa Walker

Key Points

  • This research aims to explore cognitive factors that influence older adults' willingness to receive crucial vaccines.
  • Cross-sectional study design using a representative sample of 420 older adults aged ≥60 years.
  • Utilized multistage stratified sampling from Chengdu, China.
  • Applied partial least squares structural equation modeling to analyze data.
  • Investigated associations between PMT cognitive constructs, health status, and vaccination willingness.
  • Moderate overall willingness to receive vaccines (16.7 ± 5.0 on a scale from 5-25).
  • PMT explained 57.6% of the variance in vaccination willingness.
  • Self-efficacy emerged as the strongest predictor of vaccination willingness (b = 0.396).
  • Perceived vulnerability and response efficacy were positively correlated with willingness.
  • Response cost negatively influenced vaccination willingness (b = -0.102).

Abstract

Vaccines against influenza, pneumococcal pneumonia, and herpes zoster are pivotal for infectious disease control in older adults, yet vaccination coverage remains suboptimal. Guided by Protection Motivation Theory (PMT), this cross-sectional study identified cognitive factors of overall willingness toward the three important vaccines among adults aged ≥60 y, to inform population-level intervention strategies. A representative sample of 420 older adults was recruited from Chengdu, China, via multistage stratified sampling between August and October 2024. Partial least squares structural equation modeling was applied to analyze associations between PMT cognitive constructs, health status, and overall vaccination willingness. Results showed moderate overall willingness to receive the three vaccines (16.7 ± 5.0, range: 5-25), with PMT explaining 57.6% of its variance (R2 = 0.576). Four PMT cognitive factors significantly predicted vaccination willingness: three had positive associations - perceived vulnerability (b = 0.128, p p p p p p < .05). Findings suggest that, except among older adults with poor, physical health tailored public health intervention policies to boost older adults' overall willingness for the three key vaccines should prioritize targeting vaccination-related beliefs (self-efficacy, benefits, costs, and risk of infection) rather than disease severity.

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Cite This Study

Peng et al. (2026) studied this question.

synapsesocial.com/papers/69e07bc12f7e8953b7cbd753https://doi.org/10.1080/21645515.2026.2657121
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